Slow down age related macular degeneration using your genetics

EyeGen can help build your blue print for better eye health

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Understand your Risk. Protect your family

AMD is considered one of the most powerfully genetic-dominant diseases discovered to date. Your genetic profile can account for over 60% of the risk of developing AMD. Having a first-degree relative (mother, father, brother, sister) with AMD significantly increases. Protect yourself, protect your family.

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Real Stories from AMD patients:

“While searching for a macular degeneration treatment, I took the EyeGen test and found that I had 2 copies of the CFH risk markers and no risk copies of the ARMS2 gene.  My eyecare provider immediately put me on a different supplement matching my genotype.”
F. Ferguson

Patient Testimonials
Research based on work from well-known Institutions

A different way to think about AREDs

Multiple studies have revealed that 1 in 6 people taking AREDs may actually fast track progression to more advanced stages of disease causing accelerated vision loss.

Know your genetics. Establish your personalized treatment plan.

Your genetic profile accounts for 60% of the cause of AMD while the rest is attributed to individual and environmental factors.  Many patients with AMD are taking AREDs formulations.  However, 15% of patients taking this supplement are actually increasing progression.  The EyeGen test will reveal whether you are harmed or helped by an AREDs formulation and recommend a supplement that is personalized based on your genetics.

Our lab is certified according to the College of American Pathology (CAP), the Clinical Laboratory Improvement Amendments (CLIA) and the Clinical Laboratory Evaluation Program (CLEP).

Newest 2023 Research
‍
‍A recent study published in March 2023 in the Journal of Clinical Medicine, analysed the effects of macular degeneration to: age, sex, and visual acuity. The study revealed that a genetic variant associated with CFH may cause AMD advancement over a 3-year period. This finding confirmed data from the newest meta-analyses based on pooled studies, including 17,174 individuals 45 years of age or older participating in 6 population-based cohort studies, 2 clinic-based studies and 1 case‒control study, demonstrating that CFH gene is the leading driver of late forms of AMD. 60 and 61

Krytkowska, E.; Ulańczyk, Z.; Grabowicz, A.; Safranow, K.; Kawa, M.P.; Pałucha, A.; Wąsowska, A.; Matczyńska, E.; Boguszewska-Chachulska, A.; Machalińska, A. Influence of Clinical and Genetic Factors on the Progression of Age-Related Macular Degeneration: A 3-Year Follow-Up. J. Clin. Med. 2023, 12, 1963.
https://doi.org/10.3390/jcm12051963

60. Bonyadi, M.H.J.; Yaseri, M.; Nikkhah, H.; Bonyadi, M.; Nazari, R.; Soheilian, M. Comparison of ARMS2/LOC387715 A69S and CFH Y402H risk effect in wet-type age-related macular degeneration: A meta-analysis. Int. Ophthalmol. 2018, 39, 949–956.
‍https://doi.org/10.1007/s10792-018-0853-y.\\

‍61. Colijn, J.M.; Meester-Smoor, M.; Verzijden, T.; de Breuk, A.; Silva, R.; Merle, B.M.; Cougnard-Grégoire, A.; Hoyng, C.B.; Fauser, S.; Coolen, A.; et al. Genetic Risk, Lifestyle, and Age-Related Macular Degeneration in Europe: The EYE-RISK Consortium. Ophthalmology 2020, 128, 1039–1049.
https://doi.org/10.1016/j.ophtha.2020.11.024.

EyeGen

The results from your DNA swab:

Identify those at high risk for AMD by screening for 12 genes known to be associated with AMD.
Indicate whether AREDs formulations with Zinc are harmful or helpful.
Identify the type of supplement to take to reduce vision loss progression.
$ 359
$399
Get EyeGen

Introductory offer! Complimentary 6 months supply of personalized nutritional supplements based on your genotype + 10 minute telehealth consultation ($180 value)

PLEASE NOTE: Eyegen genetic test will reveal whether you are harmed or helped by an AREDs formulation and recommend a personalized supplement with the best efficacy based on your genetics.  It's a safe and easy test that will give you the peace of mind to know you will be taking the perfect supplement to match your unique genotype. Eyegen is a macular degeneration genetic testing company and does not sell nutritional supplements nor profits from supplement recommendations.  Based on your test results, a list of companies offering appropriate supplements will be provided to you. As a limited time offer, you have the option to receive a complimentary 6 months supply of personalized Vision Elements eye supplements. Vision Elements Nutritional supplements are endorsed by leading eye care practitioners across North America. Vision Elements offers vegan-friendly, clean label ocular nutrition products in eco-conscious packaging to support patients facing retinal disease. Personalized formulations made with and without zinc, all contain the three important macular protective pigments: Lutein, Zeaxanthin, and Meso-Zeaxanthin.  Your Eyegen genetic test will determine if zinc is appropriate for your ocular nutrition regimen.
For more information about Vision Elements supplements, please visit www.visionelements.com . In Addition, you are entitled to a complimentary review of your Eyegen results with an Eye Doctor who specializes in genetics, nutrition, and macular degeneration.




Macular Degeneration Genetic Testing In The Media

Learn how AMD genetic testing is being integrated into eyecare while helping in-patient treatment

Macular degeneration runs in families. Know your genetic risk.
Protect yourself. Protect your family.

Receive a volume discount when you purchase more than 1 kit.

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How it works

1

Order EyeGen

Order your kit online.

2

Swab Your Cheeks

Follow instructions on swabbing.

3

Mail Back EyeGen

Mail the kit back to us with free postage. We’ll get it analyzed.

4

Get results

We’ll send you a code via email to check your results.

Patients that EyeGen have helped so far...

EyeGen has helped thousands of patients identify their genetic risk for Age Related Macular Degeneration and determine which supplement will provide the greatest protection

As of 2022, we’ve provided EyeGen tests to
203,502
patients
AND
identified
30,032
patients who are at risk of progression when taking an AREDs supplement
6,273,421
Patients taking some form of AREDs eye vitamins in North America
940,843
Patients taking AREDs, but are at risk for supplement induced vision loss (High CFH, Low ARMS2 gene)

The Science

Dr. Dennis Ruskin, O.D
Dr. Ruskin graduated with a degree in optometry at the University of Waterloo in 1976. In 1989 he received a fellowship with the American Academy of Optometry. Dr. Ruskin has been an appointed advisory member to various committees within the Canadian provincial government, College of Optometrists of Ontario, Ontario Association of Optometrists, pharmaceutical corporations.
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Dr. Pradeepa "Deepa" Yoganathan, MD
"Our community-based study of patients with wet, AMD demonstrates a significantly increased percentage of patients with Genotype Group 2 who took AREDS formula vitamins."
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Dr. Stephen Kaufman, MD
“For patients with dry macular degeneration, I recommend that they get genetic testing before starting AREDS2 supplements. Otherwise, I am doubtful that the benefits outweigh the risks.”
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What is Age Related Macular Degeneration (AMD)?

AMD is a progressive eye disease affecting the clear central vision needed for daily activities like reading or driving, leaving only peripheral vision intact. As toxic drusen deposits build up in the macula, cells responsible for vision begin to break down under oxidative attack, leading to poor visual function. One in five AMD cases will progress to the advance forms of the disease.

Risk Factors For Macula Degeneration

Note that Low Macular Pigment is associated with virtually every risk factor for AMD
Age
Genetics
Smoking
Diabetes
Sun Exposure
Dietary Habits
Vascular Disease
Exercise Routine

A diagnosis of AMD can be scary

Fortunately, AMD is generally a slow moving condition, and most people have an early dry forms of the disease. This buys time to make positive lifestyle changes such as improving diet, exercise habits, and adding ocular nutrition products to help maintain eyesight.

Everything you need to know about EyeGen Genetic Test

Multiple genetic research studies reveal that zinc-based eye vitamins like AREDS/AREDS2 used to prevent the progression of age-related macular degeneration (AMD) are not safe for 15% of patients. For AMD patients with a specific genotype, the risk of developing wet AMD is tripled by taking supplemental zinc formulations (25 mg per day and higher), which increases the risk of vision loss. Only an EyeGen test can identify those who have an increased risk of progression to wet AMD after exposure to zinc. This helps those with dry AMD avoid supplements that increase their risk of vision loss.  The EyeGen test also identifies those who are high risk for AMD progression. These individuals would then require increased surveillance and early referral to a specialist to help preserve their sight.

Below you’ll find answers to our most commonly asked questions. If you do not find the answer you are looking for, please contact us or call our Consumer Services team at 1-833-EYE-GEN1 (833-393-4361) weekdays from 10am-6pm EST

What happens to my DNA, and how is my privacy protected?

I already have wet/dry AMD. Why would I need to get a genetic test?

My eye care professional doesn’t know about EyeGen. What should I do?

I have early AMD. Should I take AREDS/AREDS2?

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